Structural Biology
Discovering Macromolecule Structure and Function

The Department of Structural Biology seeks to understand the structure and function of macromolecules through structure determination by X-ray crystallography, NMR, electron microscopy, theoretical analyses, and a wide range of correlative biochemical and genetic studies of function. Problems currently under study include molecular recognition by the immune system, cellular recognition by adhesion molecules, structure and activity of molecular chaperones, structure and mechanism of ribozymes, transcriptional mechanisms, and protein folding.

The department is well-equipped for experimental biochemistry and molecular biology. In addition, facilities available for structural and theoretical studies include electron microscopes, a diffractometer, a multiwire area detector and image plate for X-ray diffraction, several workstations with high-level graphics for molecular modeling and theoretical studies, a flow cytometer, a DNA sequencer, a protein sequencer and state of the art NMR facilities.

Upcoming EVents

4th of July Holiday Weekend

School of Medicine administrative offices will be closed on Thursday, July 2nd and Friday, July 3rd in observance of the Independence Day holiday. Have fun and stay safe!


Structural Molecular Biology Summer School 2009

SLAC National Accelerator Laboratory
Sept 8 - 11, 2009 (pdf)

The biennial SSRL Structural Molecular Biology (SMB) Summer School provides a lecture series and practical application workshops on biological scientific applications of synchrotron radiation. The goal of the school is to disseminate information about the scientific opportunities in synchrotron radiation applications and train participants on the theoretical aspects, data acquisition and practical data analysis of different experimental techniques. For more information, please visit their web site.

Department News
Elisabetta Viani Puglisi Named Assistant Professor of Research

Our congratulations to Dr. Elisabetta Viani Puglisi on becoming the newest faculty member of the Structural Biology Department. Her newly established lab studies the structure and functions of RNAs in viral infections. Please join us in wishing her continued distinction and success.

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